Russia as Europe's other

democracy; East-Central Europe; EU-East-Central Europe; European public space; history

Uses of the self: two ways of thinking about scholarly situatedness and method

If the scholarly self is irretrievably tied to the world, then self-situating is a fruitful source of data production. The researcher becomes a producer, as opposed to a collector, of data. This how-to paper identifies three analytical stages where such self-situating takes place. Pre-field; there is autobiographical situating; in-field, there is field situating, and post-field, there is textual situating. Each of these stages are presented in terms of the three literatures that have done the most work on them -- feminism, Gestalt, and poststructuralism – and a number of how-to examples. We illustrate with a number of how-to examples. In conclusion, we discuss how two different methodological commitments to situatedness, which Jackson (2010) dubbed reflexivist and analyticist, give rise to two analytically distinct ways of using the scholarly self for data production. Reflexivists and analyticists approach data production from opposite ends of the researcher/informant relationship. Where a reflexivist researcher tends to handle the relation between interlocutor and researcher by asking how interlocutors affect her, an analyticist researcher tends to ask how the researcher affects them

Fixed subgroups are compressed in surface groups

For a compact surface $\Sigma$ (orientable or not, and with boundary or not) we show that the fixed subgroup, $\operatorname{Fix} B$, of any family $B$ of endomorphisms of $\pi_1(\Sigma)$ is compressed in $\pi_1(\Sigma)$ i.e., $\operatorname{rk}((\operatorname{Fix} B)\cap H)\leq \operatorname{rk}(H)$ for any subgroup $\operatorname{Fix} B \leq H \leq \pi_1(\Sigma)$. On the way, we give a partial positive solution to the inertia conjecture, both for free and for surface groups. We also investigate direct products, $G$, of finitely many free and surface groups, and give a characterization of when $G$ satisfies that $\operatorname{rk}(\operatorname{Fix} \phi) \leq \operatorname{rk}(G)$ for every $\phi \in Aut(G)$

Proof of the Standard Quantum Limit for Monitoring Free-Mass Position

The measurement result of the moved distance for a free mass m during the time t between two position measurements cannot be predicted with uncertainty smaller than sqrt{hbar t/2m}. This is formulated as a standard quantum limit (SQL) and it has been proven to always hold for the following position measurement: a probe is set in a prescribed position before the measurement. Just after the interaction of the mass with the probe, the probe position is measured, and using this value, the measurement results of the pre-measurement and post-measurement positions are estimated.Comment: 4 pages, no figur

General practitioner empathy, patient enablement, and patient-reported outcomes in primary care in an area of high socio-economic deprivation in Scotland - a pilot prospective study using structural equation modelling

<b>Objective</b> The aim of this pilot prospective study was to investigate the relationships between general practitioners (GPs) empathy, patient enablement, and patient-assessed outcomes in primary care consultations in an area of high socio-economic deprivation in Scotland.<p></p> <b>Methods</b> This prospective study was carried out in a five-doctor practice in an area of high socio-economic deprivation in Scotland. Patients’ views on the consultation were gathered using the Consultation and Relational Empathy (CARE) Measure and the Patient Enablement Instrument (PEI). Changes in main complaint and well-being 1 month after the contact consultation were gathered from patients by postal questionnaire. The effect of GP empathy on patient enablement and prospective change in outcome was investigated using structural equation modelling.<p></p> <b>Results</b> 323 patients completed the initial questionnaire at the contact consultation and of these 136 (42%) completed and returned the follow-up questionnaire at 1 month. Confirmatory factor analysis confirmed the construct validity of the CARE Measure, though omission of two of the six PEI items was required in order to reach an acceptable global data fit. The structural equation model revealed a direct positive relationship between GP empathy and patient enablement at contact consultation and a prospective relationship between patient enablement and changes in main complaint and well-being at 1 month.<p></p> <b>Conclusion</b> In a high deprivation setting, GP empathy is associated with patient enablement at consultation, and enablement predicts patient-rated changes 1 month later. Further larger studies are desirable to confirm or refute these findings.<p></p> <b>Practice implications</b> Ways of increasing GP empathy and patient enablement need to be established in order to maximise patient outcomes. Consultation length and relational continuity of care are known factors; the benefit of training and support for GPs needs to be further investigate

Generation of pulse trains by current-controlled magnetic mirrors

The evolution of a spin-wave packet trapped between two direct current-carrying wires placed on the surface of a ferrite film is observed by Brillouin light scattering. The wires act as semi-transparent mirrors confining the packet. Because the spin-wave energy partially passes through these mirrors, trains of spin-wave packets are generated outside the trap. A numerical model of this process is presented and applied to the case when the current in the wires is dynamically controlled. This dynamical control of the mirror reflectivity provides new functionalities interesting for the field of spin-wave logic like that of a spin-wave memory cell.Comment: 4 pages, 3 figure

Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation

T cells are nodal players in the adaptive immune response against pathogens and malignant cells. Alternative splicing plays a crucial role in T cell activation, which is analyzed mainly at later time points upon stimulation. Here we have discovered a 2-h time window early after stimulation where optimal splicing efficiency or, more generally, gene expression efficiency is crucial for successful T cell activation. Reducing the splicing efficiency at 4 to 6 h poststimulation significantly impaired murine T cell activation, which was dependent on the expression dynamics of the Egr1-Nab2-interleukin-2 (IL-2) pathway. This time window overlaps the time of peak IL-2 de novo transcription, which, we suggest, represents a permissive time window in which decreased splicing (or transcription) efficiency reduces mature IL-2 production, thereby hampering murine T cell activation. Notably, the distinct expression kinetics of the Egr1-Nab2-IL-2 pathway between mouse and human render human T cells refractory to this vulnerability. We propose that the rational temporal modulation of splicing or transcription during peak de novo expression of key effectors can be used to fine-tune stimulation-dependent biological outcomes. Our data also show that critical consideration is required when extrapolating mouse data to the human system in basic and translational research

Measurement of the proton light response of various LAB based scintillators and its implication for supernova neutrino detection via neutrino-proton scattering

The proton light output function in electron-equivalent energy of various scintillators based on linear alkylbenzene (LAB) has been measured in the energy range from 1 MeV to 17.15 MeV for the first time. The measurement was performed at the Physikalisch-Technische Bundesanstalt (PTB) using a neutron beam with continuous energy distribution. The proton light output data is extracted from proton recoil spectra originating from neutron-proton scattering in the scintillator. The functional behavior of the proton light output is described succesfully by Birks' law with a Birks constant kB between (0.0094 +/- 0.0002) cm/MeV and (0.0098 +/- 0.0003) cm/MeV for the different LAB solutions. The constant C, parameterizing the quadratic term in the generalized Birks law, is consistent with zero for all investigated scintillators with an upper limit (95% CL) of about 10^{-7} cm^2/MeV^2. The resulting quenching factors are especially important for future planned supernova neutrino detection based on the elastic scattering of neutrinos on protons. The impact of proton quenching on the supernova event yield from neutrino-proton scattering is discussed.Comment: 12 pages, 17 figures, 4 tables, updated version for publication in Eur.Phys.J.

Response to the roundtable

I should like to thank my four interlocutors for their thoughtful responses. I will touch only briefly on the comments made by Chris Brown and Jon Mercer, since we have few outstanding issues, and concentrate on what, not unexpectedly, emerges as the major bone of contention, namely the status of physiology or biology relative to a social science like ours. I agree with Chris Brown that there is perhaps too much self-reflection relative to other kinds of analysis within the discipline, but note in my defence that the genre of the inaugural is particularly inviting of this kind of stock-taking. We only seem to have one disagreement, namely the extent to which the roads not travelled in international relations should be studied. I may be more positive on this front, both for their inherent interest (what they can tell us about variation in relations between human polities) and also for the genealogical reason that systems tend to retain the memory of negative choices. These may, therefore, prove to be important later on. While I remain sceptical about Searle’s distinction between brute and institutional facts – what is so brute about the law of gravity in societies that do not acknowledge it?1 – I am in agreement with the general thrust of Jon Mercer’s argument. Neurosciences are important for us because they can tell us more about what is common to psychological systems, and so makes it easier to pin down psychological and social variation.2 Mercer also notes, contra Johnson, that psychology and biology are indeed causally linked, but that the psychological realm is ontically separate. I concur..